Norihiro Sugino

Chairman and Professor
Division of Obstetrics and Gynecology,
Department of Reproductive, Pediatric and Infectious Science,
Yamaguchi University School of Medicine


lecturer's photo

Educational Background

1985Graduated from Yamaguchi University School of Medicine (MD)
1987-1991Postgraduate School, Yamaguchi University School of Medicine (PhD)

Occupation

1985-1986Department of Obstetrics and Gynecology, Yamaguchi University School of Medicine (Resident)
1986-1987Department of Obstetrics and Gynecology, Kyushu Kouseinennkinn Hospital, Japan (Resident)
1991-1994Department of Obstetrics and Gynecology, Sanyo Central Hospital, Yamaguchi, Japan

Research and Academic experience

1991-1994Department of Obstetrics and Gynecology, Yamaguchi University School of Medicine (Research Associate)
1994-2001Department of Obstetrics and Gynecology, Yamaguchi University School of Medicine (Research Assistant professor)
1996-1998Department of Physiology and Biophysics, University of Illinois at Chicago (post-doctoral fellow)
2001-2003Department of Obstetrics and Gynecology, Yamaguchi University School of Medicine (Assistant Professor)
2003-Department of Obstetrics and Gynecology, Yamaguchi University School of Medicine (Professor and Chairman)

Editorial Board

  • Journal of Reproduction and Development
  • Reproductive Biology of the Endocrinology

Publications (2000-2005, selected 20)

  1. Matsuoka-Sakata A, Tamura H, Asada H, Miwa I, Taketani T, Yamagata Y, Sugino N (2006) Changes in vascular leakage and expression of angiopoietins in the corpus luteum during pregnancy in rats. Reproduction, in press.
  2. Sugino N, Suzuki T, Sakata A, Miwa I Asada H Taketani T Yamagata Y, Tamura H (2005) Angiogenesis in the human corpus luteum: Changes in expression of angiopoietins in the corpus luteum throughout the menstrual cycle and in early pregnancy. J Clin Endocrinol Metab, 90: 6141-6148.
  3. Sugino N (2005) Reactive oxygen species in ovarian physiology. Reprod Med Biol, 4: 31-44.
  4. Sugino N, Karube-Harada A, Taketani T, Sakata A, Nakamura Y (2004) Withdrawal of ovarian steroids stimulates prostaglandin F2 production through nuclear factor- B activation via oxygen radicals in human endometrial stromal cells: potential relevance to menstruation. J Reprod Dev, 50: 215-225.
  5. Takiguchi S, Sugino N, Esato K, Karube-Harada A, Sakata A, Nakamura Y, Ishikawa H, Kato H (2004) Differential regulation of apoptosis in the corpus luteum of pregnancy and newly formed corpus luteum after parturition in rats. Biol Reprod, 70: 313-318.
  6. Sugino N, Karube-Harada A, Sakata A, Takiguchi S, Kato H (2002) Nuclear factor- B is required for tumor necrosis factor-alpha induced manganese superoxide dismutase expression in human endometrial stromal cells. J Clin Endocrinol Metab, 87: 3845-3850.
  7. Sugino N, Karube-Harada A, Sakata A, Takiguchi S, Kato H (2002) Different mechanisms for the induction of copper-zinc superoxide dismutase and manganese superoxide dismutase by progesterone in human endometrial stromal cells.
    Hum Reprod, 17: 1709-1714.
  8. Sugino N, Kashida S, Karube-Harada A,Takiguchi S, Kato H (2002) Expression of vascular endothelial growth factor and its receptors in the human endometrium throughout the menstrual cycle and in early pregnancy. Reproduction, 123: 379-387.
  9. Sugino N, Karube-Harada A, Kashida S, Takiguchi S, Kato H (2002) Differential regulation of copper-zinc superoxide dismutase and manganese superoxide dismutase by progesterone withdrawal in human endometrial stromal cells.
    Mol Hum Reprod, 8: 68-74.
  10. Sugino N, Kashida S, Takiguchi S, Karube-Harada A, Kato H (2001) Expression of vascular endothelial growth factor (VEGF) receptors in rat corpus luteum: regulation by oestradiol during mid-pregnancy. Reproduction, 122: 875-881.
  11. Karube-Harada A, Sugino N, Kashida S, Takiguchi S, Takayama H, Yamagata Y, Nakamura Y, Kato H (2001) Induction of manganese superoxide dismutase by tumor necrosis factor-alpha in human endometrial stromal cells. Mol Hum Reprod 7: 1065-1072.
  12. Sugino N, Karube-Harada A, Kashida S, Takiguchi S, Kato H (2001) Reactive oxygen species stimulate prostaglandin F2 production in human endometrial stromal cells in vitro. Hum Reprod, 16: 1797-1801.
  13. Muramatsu Y, Sugino N, Suzuki T, Totsue K, Takahashi T, Tashiro A, Hongo M, Oki Y, Asano H (2001) Urocortin and corticotropin-releasing factor receptor expression in normal cycling human ovaries. J Clin Endocrinol Metab, 86: 1362-1369.
  14. Kashida S, Sugino N, Takiguchi S, Karube A, Takayama H, Yamagata Y, Nakamura Y, Kato H. (2001) Regulation and role of vascular endothelial growth factor in the corpus luteum during mid-pregnancy in rats. Biol Reprod, 64: 317-323.
  15. Sugino N, Suzuki T, Kashida S, Karube A, Takiguchi S, Kato H (2000) Expression of bcl-2 and bax in the human corpus luteum during the menstrual cycle and in early pregnancy: regulation by human chorionic gonadotropin. J Clin Endocrinol Metab, 85: 4379-4386.
  16. Sugino N, Kashida S, Takiguchi S, Karube A, Kato H (2000) Expression of vascular endothelial growth factor and its receptors in the human corpus luteum during the menstrual cycle and in early pregnancy. J Clin Endocrinol Metab, 85: 3919-3924.
  17. Sugino N, Nakata M, Kashida S, Karube A, Takiguchi S, Kato H (2000) Decreased superoxide dismutase expression and increased concentrations of lipid peroxide and prostaglandin F2 in the decidua of failed pregnancy. Mol Hum Reprod, 6: 642-647.
  18. Sugino N, Kashida S, Takiguchi S, Nakamura Y, Kato H (2000) Induction of superoxide dismutase by decidualization in human endometrial stromal cells.
    Mol Hum Reprod, 6: 178-184.
  19. Sugino N, Takiguchi S, Kashida S, Karube A, Nakamura Y, Kato H (2000) Superoxide dismutase expression in the human corpus luteum during the menstrual cycle and in early pregnancy. Mol Hum Reprod, 6: 19-25.
  20. Takiguchi S, Sugino N, Kashida S, Yamagata Y, Nakamura Y, Kato H. (2000) Rescue of the corpus luteum and an increase in luteal superoxide dismutase expression induced by plcental luteotropins in the rat: action of testosterone without conversion to estrogen. Biol Reprod, 62: 398-403.


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